Is physical exercise a protective agent against the way we currently age? A narrative review.
DOI:
https://doi.org/10.59856/arch.soc.chil.med.deporte.v66i1.24Palabras clave:
Aging, functional capacity, physical exercise, quality of lifeResumen
Aging is an inherent process to living beings that involves a deterioration of homeostatic regulation and functional reserve. Currently, the aging population has high levels of physical inactivity that aggravates muscle disuse, which in turn drastically affects functional capacity and quality of life. The aim of this narrative review is to present aging conditions and the protective role of physical exercise in functional reserve and capacity in relation to how we currently age. The regular practice of physical exercise provokes several favorable responses to the preservation of neuromuscular and cardiorespiratory function, which has a direct impact on physical capacity, even benefiting cognitive function. Physical exercise has been shown to have a protective effect on different systems, apart from contributing to the preservation of functionality and self-efficacy, which is why it is essential for healthy aging, since it favors a better resolution to stressful events such as falls and/or diseases. In conclusion, even though physical exercise does not prevent the deleterious conditions of aging, its effects are positively related to the maintenance of systemic functional reserve and capacity, which translates into greater autonomy, independence and quality of life related to health in the last stage of the life cycle.
Descargas
Referencias
da Costa JP, Vitorino R, Silva GM, Vogel C, Duarte AC, Rocha-Santos T. A synopsis on aging-Theories, mechanisms and future prospects. Ageing Res Rev. 2016;29:90-112. doi:10.1016/j.arr.2016.06.005
Guarente L. Aging research-where do we stand and where are we going?. Cell. 2014;159(1):15-19. doi:10.1016/j.cell.2014.08.041
Serna E, Gambini J, Borras C, et al. Centenarians, but not octogenarians, up-regulate the expression of microRNAs [published correction appears in Sci Rep. 2013;3:1575. Mohammed, Kheira [corrected to Abdelaziz, Kheira M]]. Sci Rep. 2012;2:961. doi:10.1038/srep00961
Rodríguez Mañas L. El informe de la Organización Mundial de la Salud sobre envejecimiento y salud: un regalo para la comunidad geriátrica [The World Health Organization report on ageing and health: A gift for the geriatrics community]. Rev Esp Geriatr Gerontol. 2016;51(5):249-251. doi:10.1016/j.regg.2015.12.013
Justice JN, Cesari M, Seals DR, Shively CA, Carter CS. Comparative Approaches to Understanding the Relation Between Aging and Physical Function. J Gerontol A Biol Sci Med Sci. 2016;71(10):1243-1253. doi:10.1093/gerona/glv035
Sbardelotto ML, Costa RR, Malysz KA, et al. Improvement in muscular strength and aerobic capacities in elderly people occurs independently of physical training type or exercise model. Clinics (Sao Paulo). 2019;74:e833. doi:10.6061/clinics/2019/e833
Valenzuela PL, Morales JS, Pareja-Galeano H, et al. Physical strategies to prevent disuse-induced functional decline in the elderly. Ageing Res Rev. 2018;47:80-88. doi:10.1016/j.arr.2018.07.003
Lindahl E, Tilton K, Eickholt N, Ferguson-Stegall L. Yoga reduces perceived stress and exhaustion levels in healthy elderly individuals. Complement Ther Clin Pract. 2016;24:50-56. doi:10.1016/j.ctcp.2016.05.007
Rezola-Pardo C, Arrieta H, Gil SM, et al. A randomized controlled trial protocol to test the efficacy of a dual-task multicomponent exercise program in the attenuation of frailty in long-term nursing home residents: Aging-ONDUAL-TASK study. BMC Geriatr. 2019;19(1):6. Published 2019 Jan 8. doi:10.1186/s12877-018-1020-z
Rodríguez Rodríguez V, Rodríguez Mañas L, Sancho Castiello M, Díaz Martín R. Envejecimiento. La investigación en España y Europa [Ageing: research in Spain and Europe]. Rev Esp Geriatr Gerontol. 2012;47(4):174-179. doi:10.1016/j.regg.2012.02.005
Arai H, Ouchi Y, Yokode M, et al. Toward the realization of a better aged society: messages from gerontology and geriatrics. Geriatr Gerontol Int. 2012;12(1):16-22. doi:10.1111/j.1447-0594.2011.00776.x
Briggs AM, Cross MJ, Hoy DG, et al. Musculoskeletal Health Conditions Represent a Global Threat to Healthy Aging: A Report for the 2015 World Health Organization World Report on Ageing and Health. Gerontologist. 2016;56 Suppl 2:S243-S255. doi:10.1093/geront/gnw002
Fiuza-Luces C, Garatachea N, Berger NA, Lucia A. Exercise is the real polypill. Physiology (Bethesda). 2013;28(5):330-358. doi:10.1152/physiol.00019.2013
Daskalopoulou C, Stubbs B, Kralj C, Koukounari A, Prince M, Prina AM. Physical activity and healthy ageing: A systematic review and meta-analysis of longitudinal cohort studies. Ageing Res Rev. 2017;38:6-17. doi:10.1016/j.arr.2017.06.003
Marzetti E, Calvani R, Tosato M, et al. Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging Clin Exp Res. 2017;29(1):35-42. doi:10.1007/s40520-016-0705-4
Lopez P, Pinto RS, Radaelli R, et al. Benefits of resistance training in physically frail elderly: a systematic review. Aging Clin Exp Res. 2018;30(8):889-899. doi:10.1007/s40520-017-0863-z
Carmona JJ, Michan S. Biology of Healthy Aging and Longevity. Rev Invest Clin. 2016;68(1):7-16.
Katz S. Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. J Am Geriatr Soc. 1983;31(12):721-727. doi:10.1111/j.1532-5415.1983.tb03391.x
Andrade FB, Duarte YAO, Souza Junior PRB, Torres JL, Lima-Costa MF, Andrade FCD. Inequalities in basic activities of daily living among older adults: ELSI-Brazil, 2015. Rev Saude Publica. 2018;52Suppl 2(Suppl 2):14s. Published 2018 Oct 25. doi:10.11606/S1518-8787.2018052000617
Crombie KM, Leitzelar BN, Almassi NE, Mahoney JE, Koltyn KF. Translating a "Stand Up and Move More" intervention by state aging units to older adults in underserved communities: Protocol for a randomized controlled trial. Medicine (Baltimore). 2019;98(27):e16272. doi:10.1097/MD.0000000000016272
Mañas A, Del Pozo-Cruz B, Rodríguez-Gómez I, et al. Dose-response association between physical activity and sedentary time categories on ageing biomarkers. BMC Geriatr. 2019;19(1):270. Published 2019 Oct 15. doi:10.1186/s12877-019-1284-y
Berrazuelta-Fernández JR. Aging and Cardiovascular Diseases ANALES RANM. Real Academia Nacional de Medicina de España. An RANM. 2018; 135(03):266-280. doi:10.32440/ar.2018.135.03.rev09
Cooper R, Kuh D, Hardy R; Mortality Review Group; FALCon and HALCyon Study Teams. Objectively measured physical capability levels and mortality: systematic review and meta-analysis. BMJ. 2010;341:c4467. Published 2010 Sep 9. doi:10.1136/bmj.c4467
Klinedinst NJ, Resnick B, Yerges-Armstrong LM, Dorsey SG. The Interplay of Genetics, Behavior, and Pain with Depressive Symptoms in the Elderly. Gerontologist. 2015;55 Suppl 1(Suppl 1):S67-S77. doi:10.1093/geront/gnv015
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153(6):1194-1217. doi:10.1016/j.cell.2013.05.039
Segel M, Neumann B, Hill MFE, et al. Niche stiffness underlies the ageing of central nervous system progenitor cells [published correction appears in Nature. 2019 Aug 29;:]. Nature. 2019;573(7772):130-134. doi:10.1038/s41586-019-1484-9
Hunter SK, Pereira HM, Keenan KG. The aging neuromuscular system and motor performance. J Appl Physiol (1985). 2016;121(4):982-995. doi:10.1152/japplphysiol.00475.2016
McKinnon NB, Connelly DM, Rice CL, Hunter SW, Doherty TJ. Neuromuscular contributions to the age-related reduction in muscle power: Mechanisms and potential role of high velocity power training. Ageing Res Rev. 2017;35:147-154. doi:10.1016/j.arr.2016.09.003
Correa-de-Araujo R, Hadley E. Skeletal muscle function deficit: a new terminology to embrace the evolving concepts of sarcopenia and age-related muscle dysfunction. J Gerontol A Biol Sci Med Sci. 2014;69(5):591-594. doi:10.1093/gerona/glt208
Clark BC, Manini TM. What is dynapenia?. Nutrition. 2012;28(5):495-503. doi:10.1016/j.nut.2011.12.002
Tudoraşcu I, Sfredel V, Riza AL, Dănciulescu Miulescu R, Ianoşi SL, Dănoiu S. Motor unit changes in normal aging: a brief review. Rom J Morphol Embryol. 2014;55(4):1295-1301.
Campbell MJ, McComas AJ, Petito F. Physiological changes in ageing muscles. J Neurol Neurosurg Psychiatry. 1973;36(2):174-182. doi:10.1136/jnnp.36.2.174
Piasecki M, Ireland A, Jones DA, McPhee JS. Age-dependent motor unit remodelling in human limb muscles. Biogerontology. 2016;17(3):485-496. doi:10.1007/s10522-015-9627-3
Deschenes MR. Motor unit and neuromuscular junction remodeling with aging. Curr Aging Sci. 2011;4(3):209-220. doi:10.2174/1874609811104030209
Gordon T, Hegedus J, Tam SL. Adaptive and maladaptive motor axonal sprouting in aging and motoneuron disease. Neurol Res. 2004;26(2):174-185. doi:10.1179/016164104225013806
Edström E, Altun M, Bergman E, et al. Factors contributing to neuromuscular impairment and sarcopenia during aging. Physiol Behav. 2007;92(1-2):129-135. doi:10.1016/j.physbeh.2007.05.040
Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis [published correction appears in Age Ageing. 2019 Jul 1;48(4):601]. Age Ageing. 2019;48(1):16-31. doi:10.1093/ageing/afy169
Dodds RM, Syddall HE, Cooper R, et al. Grip strength across the life course: normative data from twelve British studies. PLoS One. 2014;9(12):e113637. Published 2014 Dec 4. doi:10.1371/journal.pone.0113637
Keller K, Engelhardt M. Strength and muscle mass loss with aging process. Age and strength loss. Muscles Ligaments Tendons J. 2014;3(4):346-350. Published 2014 Feb 24.
Maggio M, De Vita F, Fisichella A, et al. The Role of the Multiple Hormonal Dysregulation in the Onset of "Anemia of Aging": Focus on Testosterone, IGF-1, and Thyroid Hormones. Int J Endocrinol. 2015;2015:292574. doi:10.1155/2015/292574
Morton RW, Traylor DA, Weijs PJM, Phillips SM. Defining anabolic resistance: implications for delivery of clinical care nutrition. Curr Opin Crit Care. 2018;24(2):124-130. doi:10.1097/MCC.0000000000000488
Cederholm T, Barazzoni R, Austin P, et al. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017;36(1):49-64. doi:10.1016/j.clnu.2016.09.004
Jensen GL, Cederholm T, Correia MITD, et al. GLIM Criteria for the Diagnosis of Malnutrition: A Consensus Report From the Global Clinical Nutrition Community. JPEN J Parenter Enteral Nutr. 2019;43(1):32-40. doi:10.1002/jpen.1440
Hunter GR, McCarthy JP, Bamman MM. Effects of resistance training on older adults. Sports Med. 2004;34(5):329-348. doi:10.2165/00007256-200434050-00005
Strait JB, Lakatta EG. Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail Clin. 2012;8(1):143-164. doi:10.1016/j.hfc.2011.08.011
Paneni F, Diaz Cañestro C, Libby P, Lüscher TF, Camici GG. The Aging Cardiovascular System: Understanding It at the Cellular and Clinical Levels. J Am Coll Cardiol. 2017;69(15):1952-1967. doi:10.1016/j.jacc.2017.01.064
Jensen MT. Resting heart rate and relation to disease and longevity: past, present and future. Scand J Clin Lab Invest. 2019;79(1-2):108-116. doi:10.1080/00365513.2019.1566567
Wilson TM, Tanaka H. Meta-analysis of the age-associated decline in maximal aerobic capacity in men: relation to training status. Am J Physiol Heart Circ Physiol. 2000;278(3):H829-H834. doi:10.1152/ajpheart.2000.278.3.H829
Kane AE, Howlett SE. Differences in Cardiovascular Aging in Men and Women. Adv Exp Med Biol. 2018;1065:389-411. doi:10.1007/978-3-319-77932-4_25
Jakovljevic DG. Physical activity and cardiovascular aging: Physiological and molecular insights. Exp Gerontol. 2018;109:67-74. doi:10.1016/j.exger.2017.05.016
Levy WC, Cerqueira MD, Abrass IB, Schwartz RS, Stratton JR. Endurance exercise training augments diastolic filling at rest and during exercise in healthy young and older men. Circulation. 1993;88(1):116-126. doi:10.1161/01.cir.88.1.116
He ZX, Darcourt J, Camous JP, et al. Correlations of left ventricular diastolic parameters and heart rate: assessment through right ventricular pacing. Eur J Nucl Med. 1992;19(5):343-348. doi:10.1007/BF00177056
Metra M, Teerlink JR. Heart failure. Lancet. 2017;390(10106):1981-1995. doi:10.1016/S0140-6736(17)31071-1
Obas V, Vasan RS. The aging heart. Clin Sci (Lond). 2018;132(13):1367-1382. Published 2018 Jul 9. doi:10.1042/CS20171156
Wolsk E, Bakkestrøm R, Thomsen JH, et al. The Influence of Age on Hemodynamic Parameters During Rest and Exercise in Healthy Individuals. JACC Heart Fail. 2017;5(5):337-346. doi:10.1016/j.jchf.2016.10.012
Nadruz W. Myocardial remodeling in hypertension. J Hum Hypertens. 2015;29(1):1-6. doi:10.1038/jhh.2014.36
Triposkiadis F, Xanthopoulos A, Butler J. Cardiovascular Aging and Heart Failure: JACC Review Topic of the Week. J Am Coll Cardiol. 2019;74(6):804-813. doi:10.1016/j.jacc.2019.06.053
O'Rourke MF, Hashimoto J. Mechanical factors in arterial aging: a clinical perspective. J Am Coll Cardiol. 2007;50(1):1-13. doi:10.1016/j.jacc.2006.12.050
Moreau KL. Intersection between gonadal function and vascular aging in women. J Appl Physiol (1985). 2018;125(6):1881-1887. doi:10.1152/japplphysiol.00117.2018
van den Munckhof ICL, Jones H, Hopman MTE, et al. Relation between age and carotid artery intima-medial thickness: a systematic review. Clin Cardiol. 2018;41(5):698-704. doi:10.1002/clc.22934
Davy KP, Seals DR. Total blood volume in healthy young and older men. J Appl Physiol (1985). 1994;76(5):2059-2062. doi:10.1152/jappl.1994.76.5.2059
Duggal NA, Niemiro G, Harridge SDR, Simpson RJ, Lord JM. Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?. Nat Rev Immunol. 2019;19(9):563-572. doi:10.1038/s41577-019-0177-9
de Rezende LF, Rey-López JP, Matsudo VK, do Carmo Luiz O. Sedentary behavior and health outcomes among older adults: a systematic review. BMC Public Health. 2014;14:333. Published 2014 Apr 9. doi:10.1186/1471-2458-14-333
Skloot GS. The Effects of Aging on Lung Structure and Function. Clin Geriatr Med. 2017;33(4):447-457. doi:10.1016/j.cger.2017.06.001
Miller MR. Structural and physiological age-associated changes in aging lungs. Semin Respir Crit Care Med. 2010;31(5):521-527. doi:10.1055/s-0030-1265893
Hochhegger B, Meirelles GS, Irion K, et al. The chest and aging: radiological findings [published correction appears in J Bras Pneumol. 2014 Jan-Feb;40(1):98. Souza, Gustavo [added]; Meireles, Gustavo Pontes de [corrected to Meirelles, Portes]]. J Bras Pneumol. 2012;38(5):656-665. doi:10.1590/s1806-37132012000500016
Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J. 1999;13(1):197-205. doi:10.1034/j.1399-3003.1999.13a36.x
Roman MA, Rossiter HB, Casaburi R. Exercise, ageing and the lung. Eur Respir J. 2016;48(5):1471-1486. doi:10.1183/13993003.00347-2016
Skloot GS, Busse PJ, Braman SS, et al. An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma in the Elderly. Ann Am Thorac Soc. 2016;13(11):2064-2077. doi:10.1513/AnnalsATS.201608-658ST
Gosselin LE, Johnson BD, Sieck GC. Age-related changes in diaphragm muscle contractile properties and myosin heavy chain isoforms [published correction appears in Am J Respir Crit Care Med 1994 Sep;150(3):879]. Am J Respir Crit Care Med. 1994;150(1):174-178. doi:10.1164/ajrccm.150.1.8025746
Kelley RC, Ferreira LF. Diaphragm abnormalities in heart failure and aging: mechanisms and integration of cardiovascular and respiratory pathophysiology. Heart Fail Rev. 2017;22(2):191-207. doi:10.1007/s10741-016-9549-4
Janssens JP. Aging of the respiratory system: impact on pulmonary function tests and adaptation to exertion. Clin Chest Med. 2005;26(3):469-vii. doi:10.1016/j.ccm.2005.05.004
Sparrow D, Weiss ST, Vokonas PS, Cupples LA, Ekerdt DJ, Colton T. Forced vital capacity and the risk of hypertension. The Normative Aging Study. Am J Epidemiol. 1988;127(4):734-741. doi:10.1093/oxfordjournals.aje.a114854
Brandenberger C, Mühlfeld C. Mechanisms of lung aging. Cell Tissue Res. 2017;367(3):469-480. doi:10.1007/s00441-016-2511-x
Vaz Fragoso CA, Gill TM. Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function. J Gerontol A Biol Sci Med Sci. 2012;67(3):264-275. doi:10.1093/gerona/glr198
Vaz Fragoso CA, McAvay G, Van Ness PH, et al. Aging-Related Considerations When Evaluating the Forced Expiratory Volume in 1 Second (FEV1) Over Time. J Gerontol A Biol Sci Med Sci. 2016;71(7):929-934. doi:10.1093/gerona/glv201
Sharma G, Goodwin J. Effect of aging on respiratory system physiology and immunology. Clin Interv Aging. 2006;1(3):253-260. doi:10.2147/ciia.2006.1.3.253
Sorino C, Battaglia S, Scichilone N, et al. Diagnosis of airway obstruction in the elderly: contribution of the SARA study. Int J Chron Obstruct Pulmon Dis. 2012;7:389-395. doi:10.2147/COPD.S31630
Taylor BJ, Johnson BD. The pulmonary circulation and exercise responses in the elderly. Semin Respir Crit Care Med. 2010;31(5):528-538. doi:10.1055/s-0030-1265894
Braman SS, Skloot GS. Pulmonary Disease in the Aging Patient. Clin Geriatr Med. 2017;33(4):xi-xii. doi:10.1016/j.cger.2017.08.001
Betik AC, Hepple RT. Determinants of VO2 max decline with aging: an integrated perspective. Appl Physiol Nutr Metab. 2008;33(1):130-140. doi:10.1139/H07-174
Strait JB, Lakatta EG. Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail Clin. 2012;8(1):143-164. doi:10.1016/j.hfc.2011.08.011
Ekblom-Bak E, Ekblom Ö, Andersson G, et al. Decline in cardiorespiratory fitness in the Swedish working force between 1995 and 2017. Scand J Med Sci Sports. 2019;29(2):232-239. doi:10.1111/sms.13328
Fleg JL, Lakatta EG. Role of muscle loss in the age-associated reduction in VO2 max. J Appl Physiol (1985). 1988;65(3):1147-1151. doi:10.1152/jappl.1988.65.3.1147
Lawrenson L, Hoff J, Richardson RS. Aging attenuates vascular and metabolic plasticity but does not limit improvement in muscle VO(2) max. Am J Physiol Heart Circ Physiol. 2004;286(4):H1565-H1572. doi:10.1152/ajpheart.01070.2003
Tanaka H, Seals DR. Invited Review: Dynamic exercise performance in Masters athletes: insight into the effects of primary human aging on physiological functional capacity. J Appl Physiol (1985). 2003;95(5):2152-2162. doi:10.1152/japplphysiol.00320.2003
Casas Herrero Á, Cadore EL, Martínez Velilla N, Izquierdo Redin M. El ejercicio físico en el anciano frágil: una actualización [Physical exercise in the frail elderly: an update]. Rev Esp Geriatr Gerontol. 2015;50(2):74-81. doi:10.1016/j.regg.2014.07.003
Dent E, Morley JE, Cruz-Jentoft AJ, et al. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging. 2019;23(9):771-787. doi:10.1007/s12603-019-1273-z
Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-M156. doi:10.1093/gerona/56.3.m146
Del Pozo-Cruz B, Mañas A, Martín-García M, et al. Frailty is associated with objectively assessed sedentary behaviour patterns in older adults: Evidence from the Toledo Study for Healthy Aging (TSHA). PLoS One. 2017;12(9):e0183911. Published 2017 Sep 11. doi:10.1371/journal.pone.0183911
Song X, Mitnitski A, Rockwood K. Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geriatr Soc. 2010;58(4):681-687. doi:10.1111/j.1532-5415.2010.02764.x
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people [published correction appears in Lancet. 2013 Oct 19;382(9901):1328]. Lancet. 2013;381(9868):752-762. doi:10.1016/S0140-6736(12)62167-9
Robinovitch SN, Feldman F, Yang Y, et al. Video capture of the circumstances of falls in elderly people residing in long-term care: an observational study [published correction appears in Lancet. 2013 Jan 5;381(9860):28]. Lancet. 2013;381(9860):47-54. doi:10.1016/S0140-6736(12)61263-X
McClure R, Turner C, Peel N, Spinks A, Eakin E, Hughes K. Population-based interventions for the prevention of fall-related injuries in older people. Cochrane Database Syst Rev. 2005;(1):CD004441. Published 2005 Jan 25. doi:10.1002/14651858.CD004441.pub2
Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2012;(9):CD007146. Published 2012 Sep 12. doi:10.1002/14651858.CD007146.pub3
Kelsey JL, Berry SD, Procter-Gray E, et al. Indoor and outdoor falls in older adults are different: the maintenance of balance, independent living, intellect, and Zest in the Elderly of Boston Study. J Am Geriatr Soc. 2010;58(11):2135-2141. doi:10.1111/j.1532-5415.2010.03062.x
Inzitari M, Calle A, Esteve A, Casas Á, Torrents N, Martínez N. ¿Mides la velocidad de la marcha en tu práctica diaria? Una revisión [Do you measure gait speed in your daily clinical practice? A review]. Rev Esp Geriatr Gerontol. 2017;52(1):35-43. doi:10.1016/j.regg.2015.12.010
Häkkinen K, Kallinen M, Izquierdo M, et al. Changes in agonist-antagonist EMG, muscle CSA, and force during strength training in middle-aged and older people. J Appl Physiol (1985). 1998;84(4):1341-1349. doi:10.1152/jappl.1998.84.4.1341
Izquierdo M, Aguado X, Gonzalez R, López JL, Häkkinen K. Maximal and explosive force production capacity and balance performance in men of different ages. Eur J Appl Physiol Occup Physiol. 1999;79(3):260-267. doi:10.1007/s004210050504
Rodríguez-Pérez M, Abreu-Sánchez A, Rojas-Ocaña MJ, Del-Pino-Casado R. Coping strategies and quality of life in caregivers of dependent elderly relatives. Health Qual Life Outcomes. 2017;15(1):71. Published 2017 Apr 14. doi:10.1186/s12955-017-0634-8
da Silva GC, Cavalcante Neto JL. Quality of life and functional capability of elderly Brazilian women. Work. 2019;62(1):97-106. doi:10.3233/WOR-182844
Marques AI, Rosa MJ, Amorim M, et al. Study protocol: using the Q-STEPS to assess and improve the quality of physical activity programmes for the elderly. BMC Res Notes. 2012;5:171. Published 2012 Jul 9. doi:10.1186/1756-0500-5-171
The World Health Organization Quality of Life assessment (WHOQOL): position paper from the World Health Organization. Soc Sci Med. 1995;41(10):1403-1409. doi:10.1016/0277-9536(95)00112-k
Kim GM, Hong MS, Noh W. Factors affecting the health-related quality of life in community-dwelling elderly people. Public Health Nurs. 2018;35(6):482-489. doi:10.1111/phn.12530
Lee S, Cheong CH. Effect of the Physical Environment on the Health-related Quality of Life of the Low-income Korean Elderly Population. Iran J Public Health. 2018;47(12):1865-1873.
Kil SR, Lee SI, Yun SC, An HM, Jo MW. J Prev Med Public Health. 2008;41(6):434-441. doi:10.3961/jpmph.2008.41.6.434
Vanleerberghe P, De Witte N, Claes C, Schalock RL, Verté D. The quality of life of older people aging in place: a literature review. Qual Life Res. 2017;26(11):2899-2907. doi:10.1007/s11136-017-1651-0
Bashkireva AS, Bogdanova DY, Bilyk AY, Shishko AV, Kachan EY, Arutyunov VA. Adv Gerontol. 2018;31(5):743-750.
de Vries NM, van Ravensberg CD, Hobbelen JS, Olde Rikkert MG, Staal JB, Nijhuis-van der Sanden MW. Effects of physical exercise therapy on mobility, physical functioning, physical activity and quality of life in community-dwelling older adults with impaired mobility, physical disability and/or multi-morbidity: a meta-analysis. Ageing Res Rev. 2012;11(1):136-149. doi:10.1016/j.arr.2011.11.002
Lin CC, Li CI, Chang CK, et al. Reduced health-related quality of life in elders with frailty: a cross-sectional study of community-dwelling elders in Taiwan. PLoS One. 2011;6(7):e21841. doi:10.1371/journal.pone.0021841
van de Ree CLP, Landers MJF, Kruithof N, et al. Effect of frailty on quality of life in elderly patients after hip fracture: a longitudinal study. BMJ Open. 2019;9(7):e025941. Published 2019 Jul 18. doi:10.1136/bmjopen-2018-025941
Silva MR, Alberton CL, Portella EG, Nunes GN, Martin DG, Pinto SS. Water-based aerobic and combined training in elderly women: Effects on functional capacity and quality of life. Exp Gerontol. 2018;106:54-60. doi:10.1016/j.exger.2018.02.018
Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: implications for clinical practice and public health. Lancet. 2019;394(10206):1365-1375. doi:10.1016/S0140-6736(19)31786-6
Cesari M, Calvani R, Marzetti E. Frailty in Older Persons. Clin Geriatr Med. 2017;33(3):293-303. doi:10.1016/j.cger.2017.02.002
Puts MTE, Toubasi S, Andrew MK, et al. Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies. Age Ageing. 2017;46(3):383-392. doi:10.1093/ageing/afw247
Liu CK, Fielding RA. Exercise as an intervention for frailty. Clin Geriatr Med. 2011;27(1):101-110. doi:10.1016/j.cger.2010.08.001
Puts MT, Lips P, Deeg DJ. Sex differences in the risk of frailty for mortality independent of disability and chronic diseases. J Am Geriatr Soc. 2005;53(1):40-47. doi:10.1111/j.1532-5415.2005.53008.x
Mitnitski AB, Graham JE, Mogilner AJ, Rockwood K. Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatr. 2002;2:1. Published 2002 Feb 27. doi:10.1186/1471-2318-2-1
de Labra C, Guimaraes-Pinheiro C, Maseda A, Lorenzo T, Millán-Calenti JC. Effects of physical exercise interventions in frail older adults: a systematic review of randomized controlled trials. BMC Geriatr. 2015;15:154. Published 2015 Dec 2. doi:10.1186/s12877-015-0155-4
American College of Sports Medicine, Chodzko-Zajko WJ, Proctor DN, et al. American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc. 2009;41(7):1510-1530. doi:10.1249/MSS.0b013e3181a0c95c
Cadore EL, Casas-Herrero A, Zambom-Ferraresi F, et al. Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians. Age (Dordr). 2014;36(2):773-785. doi:10.1007/s11357-013-9586-z
Kramer AF, Colcombe SJ, McAuley E, Scalf PE, Erickson KI. Fitness, aging and neurocognitive function. Neurobiol Aging. 2005;26 Suppl 1:124-127. doi:10.1016/j.neurobiolaging.2005.09.009
Landi F, Marzetti E, Martone AM, Bernabei R, Onder G. Exercise as a remedy for sarcopenia. Curr Opin Clin Nutr Metab Care. 2014;17(1):25-31. doi:10.1097/MCO.0000000000000018
Hruda KV, Hicks AL, McCartney N. Training for muscle power in older adults: effects on functional abilities. Can J Appl Physiol. 2003;28(2):178-189. doi:10.1139/h03-014
Ram FS, Robinson SM, Black PN. Effects of physical training in asthma: a systematic review. Br J Sports Med. 2000;34(3):162-167. doi:10.1136/bjsm.34.3.162
Arbab-Zadeh A, Dijk E, Prasad A, et al. Effect of aging and physical activity on left ventricular compliance. Circulation. 2004;110(13):1799-1805. doi:10.1161/01.CIR.0000142863.71285.74
Peterson MJ, Giuliani C, Morey MC, et al. Physical activity as a preventative factor for frailty: the health, aging, and body composition study. J Gerontol A Biol Sci Med Sci. 2009;64(1):61-68. doi:10.1093/gerona/gln001
Giné-Garriga M, Guerra M, Unnithan VB. The effect of functional circuit training on self-reported fear of falling and health status in a group of physically frail older individuals: a randomized controlled trial. Aging Clin Exp Res. 2013;25(3):329-336. doi:10.1007/s40520-013-0048-3
Harada CN, Natelson Love MC, Triebel KL. Normal cognitive aging. Clin Geriatr Med. 2013 Nov;29(4):737-52. doi: 10.1016/j.cger.2013.07.002. PMID: 24094294; PMCID: PMC4015335.
Drey M, Sieber CC, Degens H, McPhee J, Korhonen MT, Müller K, Ganse B, Rittweger J. Relation between muscle mass, motor units and type of training in master athletes. Clin Physiol Funct Imaging. 2016 Jan;36(1):70-6. doi: 10.1111/cpf.12195. Epub 2014 Oct 24. PMID: 25345553.
Steib S, Schoene D, Pfeifer K. Dose-response relationship of resistance training in older adults: a meta-analysis. Med Sci Sports Exerc. 2010;42(5):902-914. doi:10.1249/MSS.0b013e3181c34465
Peterson MD, Sen A, Gordon PM. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sports Exerc. 2011;43(2):249-258. doi:10.1249/MSS.0b013e3181eb6265
Newman AB, Kupelian V, Visser M, et al. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci. 2006;61(1):72-77. doi:10.1093/gerona/61.1.72
Delmonico MJ, Harris TB, Visser M, et al. Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr. 2009;90(6):1579-1585. doi:10.3945/ajcn.2009.28047
Clark BC, Taylor JL, Hong SL, Law TD, Russ DW. Weaker Seniors Exhibit Motor Cortex Hypoexcitability and Impairments in Voluntary Activation. J Gerontol A Biol Sci Med Sci. 2015;70(9):1112-1119. doi:10.1093/gerona/glv030
Clark BC, Taylor JL. Age-related changes in motor cortical properties and voluntary activation of skeletal muscle. Curr Aging Sci. 2011;4(3):192-199. doi:10.2174/1874609811104030192
Anziska Y, Sternberg A. Exercise in neuromuscular disease. Muscle Nerve. 2013;48(1):3-20. doi:10.1002/mus.23771
Ogborn DI, Gardiner PF. Effects of exercise and muscle type on BDNF, NT-4/5, and TrKB expression in skeletal muscle. Muscle Nerve. 2010;41(3):385-391. doi:10.1002/mus.21503
Delezie J, Weihrauch M, Maier G, et al. BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle. Proc Natl Acad Sci U S A. 2019;116(32):16111-16120. doi:10.1073/pnas.1900544116
Edelmann E, Lessmann V, Brigadski T. Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity. Neuropharmacology. 2014;76 Pt C:610-627. doi:10.1016/j.neuropharm.2013.05.043
Panja D, Bramham CR. BDNF mechanisms in late LTP formation: A synthesis and breakdown. Neuropharmacology. 2014;76 Pt C:664-676. doi:10.1016/j.neuropharm.2013.06.024
Etnier JL, Wideman L, Labban JD, et al. The Effects of Acute Exercise on Memory and Brain-Derived Neurotrophic Factor (BDNF). J Sport Exerc Psychol. 2016;38(4):331-340. doi:10.1123/jsep.2015-0335
Lavin KM, Roberts BM, Fry CS, Moro T, Rasmussen BB, Bamman MM. The Importance of Resistance Exercise Training to Combat Neuromuscular Aging. Physiology (Bethesda). 2019;34(2):112-122. doi:10.1152/physiol.00044.2018
Stec MJ, Thalacker-Mercer A, Mayhew DL, et al. Randomized, four-arm, dose-response clinical trial to optimize resistance exercise training for older adults with age-related muscle atrophy. Exp Gerontol. 2017;99:98-109. doi:10.1016/j.exger.2017.09.018
Petrella JK, Kim JS, Tuggle SC, Bamman MM. Contributions of force and velocity to improved power with progressive resistance training in young and older adults. Eur J Appl Physiol. 2007;99(4):343-351. doi:10.1007/s00421-006-0353-z
Bickel CS, Cross JM, Bamman MM. Exercise dosing to retain resistance training adaptations in young and older adults. Med Sci Sports Exerc. 2011;43(7):1177-1187. doi:10.1249/MSS.0b013e318207c15d
Motalebi SA, Cheong LS, Iranagh JA, Mohammadi F. Effect of low-cost resistance training on lower-limb strength and balance in institutionalized seniors. Exp Aging Res. 2018;44(1):48-61. doi:10.1080/0361073X.2017.1398810
Radaelli R, Fleck SJ, Leite T, et al. Dose-response of 1, 3, and 5 sets of resistance exercise on strength, local muscular endurance, and hypertrophy. J Strength Cond Res. 2015;29(5):1349-1358. doi:10.1519/JSC.0000000000000758
Hepple RT, Rice CL. Innervation and neuromuscular control in ageing skeletal muscle. J Physiol. 2016;594(8):1965-1978. doi:10.1113/JP270561
Kelly NA, Hammond KG, Bickel CS, Windham ST, Tuggle SC, Bamman MM. Effects of aging and Parkinson's disease on motor unit remodeling: influence of resistance exercise training. J Appl Physiol (1985). 2018;124(4):888-898. doi:10.1152/japplphysiol.00563.2017
Vetrovsky T, Steffl M, Stastny P, Tufano JJ. The Efficacy and Safety of Lower-Limb Plyometric Training in Older Adults: A Systematic Review. Sports Med. 2019;49(1):113-131. doi:10.1007/s40279-018-1018-x
Van Roie E, Walker S, Van Driessche S, Delabastita T, Vanwanseele B, Delecluse C. An age-adapted plyometric exercise program improves dynamic strength, jump performance and functional capacity in older men either similarly or more than traditional resistance training. PLoS One. 2020;15(8):e0237921. Published 2020 Aug 25. doi:10.1371/journal.pone.0237921
Singh H, Kim D, Kim E, et al. Jump test performance and sarcopenia status in men and women, 55 to 75 years of age. J Geriatr Phys Ther. 2014;37(2):76-82. doi:10.1519/JPT.0b013e3182a51b11
European Society of Cardiology. "Ability to lift weights quickly can mean a longer life: Not all weight lifting produces the same benefit." ScienceDaily. ScienceDaily, 12 April 2019. .
Harber MP, Konopka AR, Undem MK, et al. Aerobic exercise training induces skeletal muscle hypertrophy and age-dependent adaptations in myofiber function in young and older men. J Appl Physiol (1985). 2012;113(9):1495-1504. doi:10.1152/japplphysiol.00786.2012
He F, Li J, Liu Z, Chuang CC, Yang W, Zuo L. Redox Mechanism of Reactive Oxygen Species in Exercise. Front Physiol. 2016;7:486. Published 2016 Nov 7. doi:10.3389/fphys.2016.00486
Latini A, Pereira PJS, Couture R, Campos MM, Talbot S. Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration. Oxid Med Cell Longev. 2019;2019:2715326. Published 2019 Jan 6. doi:10.1155/2019/2715326
Powers SK, Deminice R, Ozdemir M, Yoshihara T, Bomkamp MP, Hyatt H. Exercise-induced oxidative stress: Friend or foe?. J Sport Health Sci. 2020;9(5):415-425. doi:10.1016/j.jshs.2020.04.001
Mian OS, Thom JM, Ardigò LP, Narici MV, Minetti AE. Metabolic cost, mechanical work, and efficiency during walking in young and older men. Acta Physiol (Oxf). 2006;186(2):127-139. doi:10.1111/j.1748-1716.2006.01522.x
Mian OS, Thom JM, Ardigò LP, Morse CI, Narici MV, Minetti AE. Effect of a 12-month physical conditioning programme on the metabolic cost of walking in healthy older adults. Eur J Appl Physiol. 2007;100(5):499-505. doi:10.1007/s00421-006-0141-9
Garatachea N, Pareja-Galeano H, Sanchis-Gomar F, et al. Exercise attenuates the major hallmarks of aging. Rejuvenation Res. 2015;18(1):57-89. doi:10.1089/rej.2014.1623
Garber CE, Blissmer B, Deschenes MR, et al. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43(7):1334-1359. doi:10.1249/MSS.0b013e318213fefb
Kramer A, Gollhofer A, Armbrecht G, Felsenberg D, Gruber M. How to prevent the detrimental effects of two months of bed-rest on muscle, bone and cardiovascular system: an RCT. Sci Rep. 2017;7(1):13177. Published 2017 Oct 13. doi:10.1038/s41598-017-13659-8
Sharman JE, Smart NA, Coombes JS, Stowasser M. Exercise and sport science australia position stand update on exercise and hypertension. J Hum Hypertens. 2019;33(12):837-843. doi:10.1038/s41371-019-0266-z
Williams MA, Haskell WL, Ades PA, et al. Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific statement from the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2007;116(5):572-584. doi:10.1161/CIRCULATIONAHA.107.185214
Gries KJ, Raue U, Perkins RK, et al. Cardiovascular and skeletal muscle health with lifelong exercise. J Appl Physiol (1985). 2018;125(5):1636-1645. doi:10.1152/japplphysiol.00174.2018
Heckman GA, McKelvie RS. Cardiovascular aging and exercise in healthy older adults. Clin J Sport Med. 2008;18(6):479-485. doi:10.1097/JSM.0b013e3181865f03
Kitzman DW, Brubaker PH, Herrington DM, et al. Effect of endurance exercise training on endothelial function and arterial stiffness in older patients with heart failure and preserved ejection fraction: a randomized, controlled, single-blind trial. J Am Coll Cardiol. 2013;62(7):584-592. doi:10.1016/j.jacc.2013.04.033
Coats AJS, Forman DE, Haykowsky M, et al. Physical function and exercise training in older patients with heart failure. Nat Rev Cardiol. 2017;14(9):550-559. doi:10.1038/nrcardio.2017.70
Schüttler D, Clauss S, Weckbach LT, Brunner S. Molecular Mechanisms of Cardiac Remodeling and Regeneration in Physical Exercise. Cells. 2019;8(10):1128. Published 2019 Sep 23. doi:10.3390/cells8101128
Pescatello LS, Franklin BA, Fagard R, et al. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc. 2004;36(3):533-553. doi:10.1249/01.mss.0000115224.88514.3ª
Billinger SA, Mattlage AE, Ashenden AL, Lentz AA, Harter G, Rippee MA. Aerobic exercise in subacute stroke improves cardiovascular health and physical performance. J Neurol Phys Ther. 2012;36(4):159-165. doi:10.1097/NPT.0b013e318274d082
Pinto RR, Karabulut M, Poton R, Polito MD. Acute resistance exercise with blood flow restriction in elderly hypertensive women: haemodynamic, rating of perceived exertion and blood lactate. Clin Physiol Funct Imaging. 2018;38(1):17-24. doi:10.1111/cpf.12376
Hotta K, Behnke BJ, Arjmandi B, et al. Daily muscle stretching enhances blood flow, endothelial function, capillarity, vascular volume and connectivity in aged skeletal muscle. J Physiol. 2018;596(10):1903-1917. doi:10.1113/JP275459
Rognmo Ø, Moholdt T, Bakken H, et al. Cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation. 2012;126(12):1436-1440. doi:10.1161/CIRCULATIONAHA.112.123117
Wisløff U, Støylen A, Loennechen JP, et al. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation. 2007;115(24):3086-3094. doi:10.1161/CIRCULATIONAHA.106.675041
Watsford ML, Murphy AJ, Pine MJ, Coutts AJ. The effect of habitual exercise on respiratory- muscle function in older adults. J Aging Phys Act. 2005;13(1):34-44. doi:10.1123/japa.13.1.34
Chlif M, Chaouachi A, Ahmaidi S. Effect of Aerobic Exercise Training on Ventilatory Efficiency and Respiratory Drive in Obese Subjects. Respir Care. 2017;62(7):936-946. doi:10.4187/respcare.04923
Messaggi-Sartor M, Marco E, Martínez-Téllez E, et al. Combined aerobic exercise and high-intensity respiratory muscle training in patients surgically treated for non-small cell lung cancer: a pilot randomized clinical trial. Eur J Phys Rehabil Med. 2019;55(1):113-122. doi:10.23736/S1973-9087.18.05156-0
Kerti M, Balogh Z, Kelemen K, Varga JT. The relationship between exercise capacity and different functional markers in pulmonary rehabilitation for COPD. Int J Chron Obstruct Pulmon Dis. 2018;13:717-724. Published 2018 Feb 28. doi:10.2147/COPD.S153525
Roberts MH, Mapel DW, Bruse S, Petersen H, Nyunoya T. Development of a modified BODE index as a mortality risk measure among older adults with and without chronic obstructive pulmonary disease. Am J Epidemiol. 2013;178(7):1150-1160. doi:10.1093/aje/kwt087
Smith JR, Cross TJ, Van Iterson EH, Johnson BD, Olson TP. Resistive and elastic work of breathing in older and younger adults during exercise. J Appl Physiol (1985). 2018;125(1):190-197. doi:10.1152/japplphysiol.01105.2017
Laurent H, Aubreton S, Galvaing G, et al. Preoperative respiratory muscle endurance training improves ventilatory capacity and prevents pulmonary postoperative complications after lung surgery. Eur J Phys Rehabil Med. 2020;56(1):73-81. doi:10.23736/S1973-9087.19.05781-2
Hanada M, Kasawara KT, Mathur S, et al. Aerobic and breathing exercises improve dyspnea, exercise capacity and quality of life in idiopathic pulmonary fibrosis patients: systematic review and meta-analysis. J Thorac Dis. 2020;12(3):1041-1055. doi:10.21037/jtd.2019.12.27
Wada JT, Borges-Santos E, Porras DC, et al. Effects of aerobic training combined with respiratory muscle stretching on the functional exercise capacity and thoracoabdominal kinematics in patients with COPD: a randomized and controlled trial. Int J Chron Obstruct Pulmon Dis. 2016;11:2691-2700. Published 2016 Oct 28. doi:10.2147/COPD.S114548
Langer D, Ciavaglia C, Faisal A, et al. Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD. J Appl Physiol (1985). 2018;125(2):381-392. doi:10.1152/japplphysiol.01078.2017
López-de-Uralde-Villanueva I, Candelas-Fernández P, de-Diego-Cano B, Mínguez-Calzada O, Del Corral T. The effectiveness of combining inspiratory muscle training with manual therapy and a therapeutic exercise program on maximum inspiratory pressure in adults with asthma: a randomized clinical trial. Clin Rehabil. 2018;32(6):752-765. doi:10.1177/0269215517751587
Basso-Vanelli RP, Di Lorenzo VA, Labadessa IG, et al. Effects of Inspiratory Muscle Training and Calisthenics-and-Breathing Exercises in COPD With and Without Respiratory Muscle Weakness. Respir Care. 2016;61(1):50-60. doi:10.4187/respcare.03947
McNamara RJ, Houben-Wilke S, Franssen FME, et al. Determinants of functional, peak and endurance exercise capacity in people with chronic obstructive pulmonary disease. Respir Med. 2018;138:81-87. doi:10.1016/j.rmed.2018.03.032
Aslan GK, Akinci B, Yeldan I, Okumus G. Respiratory muscle strength in patients with pulmonary hypertension: The relationship with exercise capacity, physical activity level, and quality of life. Clin Respir J. 2018;12(2):699-705. doi:10.1111/crj.12582
Kim BS, Kim JH, Park SH, Seo HS, Lee HS, Lee MM. Effect of a Respiratory Training Program Using Wind Instruments on Cardiopulmonary Function, Endurance, and Quality of Life of Elderly Women. Med Sci Monit. 2018;24:5271-5278. Published 2018 Jul 29. doi:10.12659/MSM.909492
Lee PG, Jackson EA, Richardson CR. Exercise Prescriptions in Older Adults. Am Fam Physician. 2017;95(7):425-432.
Cadore EL, Rodríguez-Mañas L, Sinclair A, Izquierdo M. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: a systematic review. Rejuvenation Res. 2013;16(2):105-114. doi:10.1089/rej.2012.1397
Lange E, Kucharski D, Svedlund S, et al. Effects of Aerobic and Resistance Exercise in Older Adults With Rheumatoid Arthritis: A Randomized Controlled Trial. Arthritis Care Res (Hoboken). 2019;71(1):61-70. doi:10.1002/acr.23589
Ferraz DD, Trippo KV, Duarte GP, Neto MG, Bernardes Santos KO, Filho JO. The Effects of Functional Training, Bicycle Exercise, and Exergaming on Walking Capacity of Elderly Patients With Parkinson Disease: A Pilot Randomized Controlled Single-blinded Trial. Arch Phys Med Rehabil. 2018;99(5):826-833. doi:10.1016/j.apmr.2017.12.014
Daly RM. Exercise and nutritional approaches to prevent frail bones, falls and fractures: an update. Climacteric. 2017;20(2):119-124. doi:10.1080/13697137.2017.1286890
Fiogbé E, de Vassimon-Barroso V, de Medeiros Takahashi AC. Exercise training in older adults, what effects on muscle oxygenation? A systematic review. Arch Gerontol Geriatr. 2017;71:89-98. doi:10.1016/j.archger.2017.03.001
Moreira NB, da Silva LP, Rodacki ALF. Aquatic exercise improves functional capacity, perceptual aspects, and quality of life in older adults with musculoskeletal disorders and risk of falling: A randomized controlled trial. Exp Gerontol. 2020;142:111135. doi:10.1016/j.exger.2020.111135
Liu CJ, Chang WP, Araujo de Carvalho I, Savage KEL, Radford LW, Amuthavalli Thiyagarajan J. Effects of physical exercise in older adults with reduced physical capacity: meta-analysis of resistance exercise and multimodal exercise. Int J Rehabil Res. 2017;40(4):303-314. doi:10.1097/MRR.0000000000000249
Mendonca GV, Pezarat-Correia P, Vaz JR, Silva L, Almeida ID, Heffernan KS. Impact of Exercise Training on Physiological Measures of Physical Fitness in the Elderly. Curr Aging Sci. 2016;9(4):240-259. doi:10.2174/1874609809666160426120600
Zambom-Ferraresi F, Cebollero P, Gorostiaga EM, et al. Effects of Combined Resistance and Endurance Training Versus Resistance Training Alone on Strength, Exercise Capacity, and Quality of Life in Patients With COPD. J Cardiopulm Rehabil Prev. 2015;35(6):446-453. doi:10.1097/HCR.0000000000000132
Bartlett DB, Willis LH, Slentz CA, et al. Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study. Arthritis Res Ther. 2018;20(1):127. Published 2018 Jun 14. doi:10.1186/s13075-018-1624-x
Van Roie E, Walker S, Van Driessche S, et al. Training load does not affect detraining's effect on muscle volume, muscle strength and functional capacity among older adults. Exp Gerontol. 2017;98:30-37. doi:10.1016/j.exger.2017.07.017
Casas-Herrero A, Anton-Rodrigo I, Zambom-Ferraresi F, et al. Effect of a multicomponent exercise programme (VIVIFRAIL) on functional capacity in frail community elders with cognitive decline: study protocol for a randomized multicentre control trial. Trials. 2019;20(1):362. Published 2019 Jun 17. doi:10.1186/s13063-019-3426-0
Reid KJ, Baron KG, Lu B, Naylor E, Wolfe L, Zee PC. Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia. Sleep Med. 2010;11(9):934-940. doi:10.1016/j.sleep.2010.04.014
Awick EA, Ehlers DK, Aguiñaga S, Daugherty AM, Kramer AF, McAuley E. Effects of a randomized exercise trial on physical activity, psychological distress and quality of life in older adults. Gen Hosp Psychiatry. 2017;49:44-50. doi:10.1016/j.genhosppsych.2017.06.005
Jönsson T, Ekvall Hansson E, Thorstensson CA, Eek F, Bergman P, Dahlberg LE. The effect of education and supervised exercise on physical activity, pain, quality of life and self-efficacy - an intervention study with a reference group. BMC Musculoskelet Disord. 2018;19(1):198. Published 2018 Jun 21. doi:10.1186/s12891-018-2098-3
Rugbeer N, Ramklass S, Mckune A, van Heerden J. The effect of group exercise frequency on health related quality of life in institutionalized elderly. Pan Afr Med J. 2017;26:35. Published 2017 Jan 24. doi:10.11604/pamj.2017.26.35.10518
Tomas-Carus P, Ortega-Alonso A, Pietilainen KH, et al. A randomized controlled trial on the effects of combined aerobic-resistance exercise on muscle strength and fatigue, glycemic control and health-related quality of life of type 2 diabetes patients. J Sports Med Phys Fitness. 2016;56(5):572-578.
Bartels EM, Juhl CB, Christensen R, et al. Aquatic exercise for the treatment of knee and hip osteoarthritis. Cochrane Database Syst Rev. 2016;3:CD005523. Published 2016 Mar 23. doi:10.1002/14651858.CD005523.pub3
Dohrn IM, Hagströmer M, Hellénius ML, Ståhle A. Short- and Long-Term Effects of Balance Training on Physical Activity in Older Adults With Osteoporosis: A Randomized Controlled Trial. J Geriatr Phys Ther. 2017;40(2):102-111. doi:10.1519/JPT.0000000000000077
Paulo TRS, Rossi FE, Viezel J, et al. The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: a randomized controlled trial. Health Qual Life Outcomes. 2019;17(1):17. Published 2019 Jan 18. doi:10.1186/s12955-019-1090-4
Odynets T, Briskin Y, Todorova V. Effects of Different Exercise Interventions on Quality of Life in Breast Cancer Patients: A Randomized Controlled Trial. Integr Cancer Ther. 2019;18:1534735419880598. doi:10.1177/1534735419880598
López-Torres Hidalgo J; DEP-EXERCISE Group. Effectiveness of physical exercise in the treatment of depression in older adults as an alternative to antidepressant drugs in primary care. BMC Psychiatry. 2019;19(1):21. Published 2019 Jan 14. doi:10.1186/s12888-018-1982-6
Kaushal N, Desjardins-Crépeau L, Langlois F, Bherer L. The Effects of Multi-Component Exercise Training on Cognitive Functioning and Health-Related Quality of Life in Older Adults. Int J Behav Med. 2018;25(6):617-625. doi:10.1007/s12529-018-9733-0
Kekäläinen T, Kokko K, Sipilä S, Walker S. Effects of a 9-month resistance training intervention on quality of life, sense of coherence, and depressive symptoms in older adults: randomized controlled trial. Qual Life Res. 2018;27(2):455-465. doi:10.1007/s11136-017-1733-z
Pedersen MT, Vorup J, Nistrup A, et al. Effect of team sports and resistance training on physical function, quality of life, and motivation in older adults. Scand J Med Sci Sports. 2017;27(8):852-864. doi:10.1111/sms.12823
Neumann S, Meidert U, Barberà-Guillem R, Poveda-Puente R, Becker H. Effects of an Exergame Software for Older Adults on Fitness, Activities of Daily Living Performance, and Quality of Life. Games Health J. 2018;7(5):341-346. doi:10.1089/g4h.2017.0079
Bjerk M, Brovold T, Skelton DA, Bergland A. A falls prevention programme to improve quality of life, physical function and falls efficacy in older people receiving home help services: study protocol for a randomised controlled trial. BMC Health Serv Res. 2017;17(1):559. Published 2017 Aug 14. doi:10.1186/s12913-017-2516-5
Chittrakul J, Siviroj P, Sungkarat S, Sapbamrer R. Multi-System Physical Exercise Intervention for Fall Prevention and Quality of Life in Pre-Frail Older Adults: A Randomized Controlled Trial. Int J Environ Res Public Health. 2020;17(9):3102. Published 2020 Apr 29. doi:10.3390/ijerph17093102
Descargas
Publicado
Número
Sección
Licencia
Derechos de autor 2021 Archivos de la Sociedad Chilena de Medicina del Deporte

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.